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CJC-1295 NO DAC + Ipamorelin
GHRH + GHS-R1a · dual pathway blend
Purity ≥98% HPLC Analysis Warehouse in Poland
159,00 PLN
Załóż konto i zbieraj punkty za zakupy — za ten produkt otrzymasz 159 pkt
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In stock · Ships in 1-2 days · InPost / Courier · BLIK payment
Cold storage at -20°C
Certificate of Analysis (CoA)
BLIK payment
14-day returns
For research use only. Not for human use.
Wyłącznie do celów badawczych. Nie do użytku ludzkiego.
Wyłącznie do celów badawczych. Nie do użytku ludzkiego.
Product Description
Physicochemical Properties
CJC-1295 NO DAC (Mod GRF 1-29)
| Parameter | Value |
|---|---|
| Molecular formula | C₁₅₂H₂₅₂N₄₄O₄₂ |
| Molecular weight | ~3367.9 Da |
| Amino acid count | 29 |
| CAS number | 863288-34-0 |
| PubChem CID | 56841945 |
| Purity | >98% (RP-HPLC) |
| Classification | Chemical reagent / research material |
| Intended use | For in vitro research use only, not for use in humans or animals |
Ipamorelin
| Parameter | Value |
|---|---|
| Molecular formula | C₃₈H₄₉N₉O₅ |
| Molecular weight | ~711.85 Da |
| Amino acid count | 5 (pentapeptide) |
| CAS number | 170851-70-4 |
| PubChem CID | 9831659 |
| Purity | >98% (RP-HPLC) |
Not classified as a hazardous substance under CLP regulation. Offered as a chemical reagent for in vitro laboratory use, within the framework of applicable European Union chemical substances regulations (REACH, CLP).
In Vitro Laboratory Use
Reconstitution and storage conditions:
- Dissolve in sterile water or phosphate buffer (recommended pH 6.0–7.4); working concentration per analytical protocol
- Storage of unreconstituted powder: −20 °C, dry location, protected from light
- After reconstitution: aliquots in microtubes, single thaw, short-term storage at 2–8 °C
Typical analytical equipment:
- HPLC column dedicated to peptide analysis (e.g., C18, 150–250 mm)
- HPLC system with detector (UV 220 nm, FLD or MS — depending on protocol)
- Autosampler vials, laboratory test tubes, precision pipettes
- Analytical balance with ≥0.1 mg accuracy for sample weighing
All working parameters should be selected according to the research laboratory’s internal protocol. Product intended exclusively for in vitro and analytical use; not for human or animal use.
Scientific Research & Details
Expand research overview
Scientific Research & Details
Expand research overviewGHRH + GHS Blend Concept
Research on the somatotropic axis has revealed two distinct pathways stimulating growth hormone secretion from pituitary somatotrophs. The first pathway is activated by the GHRH-R receptor, targeted by CJC-1295 NO DAC (Mod GRF 1-29, 29 amino acids). The second pathway utilizes the GHS-R1a receptor, stimulated by Ipamorelin (selective pentapeptide, 5 amino acids).
Combining both peptides in a single vial eliminates the need for two separate reconstitutions. CJC-1295 NO DAC provides pulsatile GHRH-R activation, while Ipamorelin exhibits high selectivity for GHS-R1a without affecting ACTH, cortisol, or prolactin release.
Component Comparison
| Parameter | CJC-1295 NO DAC | Ipamorelin |
|---|---|---|
| Peptide type | GHRH analog (Mod GRF 1-29) | GH secretagogue (pentapeptide) |
| Target receptor | GHRH-R (Gs protein) | GHS-R1a (Gq protein) |
| Signaling pathway | cAMP → PKA | PLC → IP3/DAG → Ca²⁺ |
| Selectivity | GHRH-R specific | Selective GHS-R1a (no ACTH/cortisol) |
| Molecular weight | ~3367.9 Da | ~711.85 Da |
| Amino acids | 29 | 5 |
Both components also available separately: CJC-1295 NO DAC and Ipamorelin.
Peptide Complementarity
CJC-1295 NO DAC and Ipamorelin act on the somatotropic axis through two independent receptor pathways:
- CJC-1295 NO DAC — GHRH-R receptor → stimulates GH synthesis and secretion by somatotrophs
- Ipamorelin — GHS-R1a (ghrelin) receptor → amplifies GH pulse through a distinct signaling mechanism
Action on two different receptors provides the basis for combining GHRH analogs with GHS secretagogues in GH-IGF-1 axis research. In animal models, this combination has been shown to produce GH responses 5 to 10 times greater than either peptide alone.
Stability and Storage
Both blend components maintain stability in a single lyophilized vial at -20°C. After reconstitution in sterile water, store at 2-8°C and use within 30 days.
Bibliography
2 scientific publications
Bibliography
2 scientific publicationsSelected publications on GHRH-GHS synergy in the somatotropic axis.
"Ipamorelin, the first selective growth hormone secretagogue"
European Journal of Endocrinology, 139(5):552-561
"Once-daily administration of CJC-1295 normalizes growth in GH-deficient adult rats"
Journal of Pharmacology and Experimental Therapeutics, 309:984-992
Regulatory Information and Storage Conditions
Expand
Regulatory Information and Storage Conditions
ExpandIntended Use
This product is a chemical raw material intended exclusively for in vitro research, scientific, and analytical applications. It is not intended for human or veterinary use, including for diagnostic, therapeutic, prophylactic, or nutritional purposes.
Handling
- Work in laboratory conditions consistent with Good Laboratory Practice (GLP) principles.
- Use appropriate personal protective equipment: nitrile gloves, safety goggles, lab coat.
- Avoid inhalation of dust and contact with skin or mucous membranes.
- Work in a well-ventilated area.
Regulatory Classification
This product is not classified as a hazardous substance under CLP Regulation (EC) No 1272/2008. It is offered as a chemical reagent within the framework of applicable European Union chemical substances regulations (REACH, CLP). It does not constitute a medicinal product, dietary supplement, medical device, or cosmetic within the meaning of applicable laws.
Disposal
Unused material should be disposed of in accordance with local regulations on chemical waste. Under laboratory conditions: neutralize and dispose with laboratory waste streams. Do not discharge into sewage systems.
Regulatory Information
This product is offered in accordance with applicable European Union regulations on chemical substances (REACH, CLP) and Polish law governing the trade of chemical reagents and research materials. Full terms of sale and product classification are set out in the Terms of Service.
By placing an order, the Customer confirms having read the above information and accepts the provisions of the Terms.
Safety Contact
For questions regarding handling or regulatory information: [email protected].
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Frequently Asked Questions
This blend combines two complementary peptides in one vial: CJC-1295 NO DAC (a GHRH receptor analog) and Ipamorelin (a selective GHS-R1a agonist). The combination targets two convergent pathways of the somatotropic axis.
The blend offers convenience — a single reconstitution instead of two. Both peptides are the same purity (≥98% HPLC) as our individual products. Individual CJC-1295 NO DAC and Ipamorelin are also available separately.
Store lyophilized blend at -20°C to -80°C. After reconstitution, store at 2-8°C and use within 30 days.
Available in blend variants combining CJC-1295 NO DAC and Ipamorelin. Check the variant selector above for current options.
Yes. All peptides ship from our temperature-controlled facility in Poland with next-day delivery via InPost. Free shipping on orders over 299 PLN.